肝脏 ›› 2022, Vol. 27 ›› Issue (5): 580-583.

• 其他肝病 • 上一篇    下一篇

外伤性肝破裂患者腹腔镜下修补术后并发症的危险因素研究

陈之强, 杨琦, 彭正, 陈艳军   

  1. 101300 北京市顺义区医院肝胆外科(陈之强,杨琦,彭正);郑州大学第五附属医院肝胆胰腺外科(陈艳军)
  • 收稿日期:2021-11-10 出版日期:2022-05-31 发布日期:2022-07-13
  • 通讯作者: 陈之强
  • 基金资助:
    北京市自然科学基金资助项目(7151729)

Risk factors of complications after laparoscopic repair in patients with traumatic liver rupture

CHEN Zhi-qiang1, YANG Qi1, PENG Zheng1, CHEN Yan-jun2   

  1. 1. Department of Hepatobiliary Surgery, Shunyi District Hospital of Beijing, Beijing 101300, China;
    2. Department of Hepatobiliary and Pancreatic Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Henan 450052, China
  • Received:2021-11-10 Online:2022-05-31 Published:2022-07-13
  • Contact: CHEN Zhi-qiang

摘要: 目的 研究外伤性肝破裂患者腹腔镜修补术后并发症的危险因素。方法 收集2017年4月至2020年10月本院102例外伤性肝破裂患者作为研究对象,患者均接受腹腔镜下修补术,记录并发症发生情况。采用Logistic多因素分析法探讨其术后并发症的危险因素,并建立指数方程,分析其判断并发症的应用价值。结果 102例患者中,共发生并发症38例,发生率为37.25%,其中术后感染14例,术后胆漏12例,出血8例,肝脓肿4例。Logistic多因素分析结果显示,受伤至入院时间、失血量、低血压持续时间及Alb水平是影响术后并发症的独立影响因素(P<0.05)。根据Logistic多因素分析结果建立指数方程Y=0.603X1+0.654X2+0.471X3+0.798X4+0.899X5(X1=受伤至入院时间,X2=失血量,X3=肝破裂分级,X4=低血压持续时间,X5=Alb)。ROC分析结果显示指数方程判断术后并发症的AUC为0.796(SE=0.066,95%CI=0.666~0.926,P<0.001)。结论 外伤性肝破裂患者腹腔镜下修补术后并发症发生率较高,其并发症与受伤至入院时间、失血量、肝破裂分级、低血压持续时间及Alb水平相关。

关键词: 外伤性肝破裂, 腹腔镜下修补术, 并发症, 危险因素

Abstract: Objective To study the risk factors of complications after laparoscopic repair in patients with traumatic liver rupture. Methods 102 patients with traumatic liver rupture in our hospital from April 2017 to October 2020 were collected as the research objects, all patients underwent laparoscopic repair, and the complications were recorded. The Logistic multivariate analysis was used to explore the risk factors of postoperative complications, the exponential equation was established and its application value in judging complications was analyzed. Results There were 38 cases with complications, the incidence rate was 37.25%. Among the 102 patients, there were 14 cases of postoperative infection, 12 cases of postoperative bile leakage, 8 cases of bleeding and 4 cases of liver abscess. The Logistic multivariate analysis showed that the time from injury to admission, blood loss, duration of hypotension and albumin (Alb) level were independent factors, which affected the postoperative complications (P<0.05). The exponential equation was established, which accorded to the results of the Logistic multifactor analysis: Y=0.603X1+0.654X2+0.471X3+0.798X4+0.899X5 (X1=time from injury to admission, X2=blood loss, X3=grade of liver rupture, X4=duration of hypotension, X5=Alb). Receiver operating characteristic (ROC) analysis showed that the area under curve (AUC) of postoperative complications judged by exponential equation was 0.796 (SE=0.066, 95%CI=0.666-0.926, P<0.001). Conclusion The incidence of complications after laparoscopic repair of traumatic liver rupture is high. The complications are related to the time from injury to admission, blood loss, grade of liver rupture, the duration of hypotension and Alb level.

Key words: Traumatic liver rupture, Laparoscopic repair, Complication, Risk factors