[1] Bernal W, Jalan R, Quaglia A, et al. Acute-on-chronic liver failure. Lancet. 2015, 386: 1576-1587. [2] 李伟建,杨秋蕊,王振宇,等. 生物人工肝的研究现状与进展. 肝脏, 2018: 80-83. [3] Finkenstedt A, Nachbaur K, Zoller H, et al. Acute-on-chronic liver failure: excellent outcomes after liver transplantation but high mortality on the wait list. Liver Transpl. 2013, 19: 879-886. [4] 江涛. 肝移植供肝来源的现状与进展. 世界最新医学信息文摘, 2016, 78: 43-44. [5] Shi XL, Gao Y, Yan Y, et al. Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes. Cell Res, 2016, 26: 206-216. [6] Struecker B, Raschzok N, Sauer IM. Liver support strategies: cutting-edge technologies. Nat Rev Gastroenterol Hepatol, 2014, 11: 166-176. [7] Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science, 1998, 282: 1145-1147. [8] Hopkinson BM, Desler C, Kalisz M, et al. Bioenergetic changes during differentiation of human embryonic stem cells along the hepatic lineage. Oxid Med Cell Longev, 2017, 2017: 5080128. [9] Mandal A, Raju S, Viswanathan C. Cryopreserved hepatic progenitor cells derived from human embryonic stem cells can arrest progression of liver fibrosis in rats. Cell Biol Int, 2016, 40: 1107-1115. [10] Centeno E, Cimarosti H, Bithell A. 2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling. Mol Neurodegener, 2018, 13: 27. [11] Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell, 2007, 131: 861-872. [12] Takebe T, Sekine K, Kimura M, et al. Massive and reproducible production of liver buds entirely from human pluripotent stem cells. Cell Rep, 2017, 21: 2661-2670. [13] Rashidi H, Luu NT, Alwahsh SM, et al. 3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo. Arch Toxicol, 2018, 92: 3117-3129. [14] Brady K, Dickinson SC, Guillot PV, et al. Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis. Stem Cells Dev, 2014, 23: 541-554. [15] Guillot PV, Abass O, Bassett JH, et al. Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice. Blood, 2008, 111: 1717-1725. [16] Yang HM, Cho MR, Sung JH, et al. The effect of human fetal liver-derived mesenchymal stem cells on CD34+ hematopoietic stem cell repopulation in NOD/Shi-scid/IL-2Ra(null) mice. Transplant Proc, 2011, 43: 2004-2008. [17] Ranzoni AM, Corcelli M, Hau KL, et al. Counteracting bone fragility with human amniotic mesenchymal stem cells. Sci Rep, 2016, 6: 39656. [18] In TAP, Scherjon SA, Kleijburg-Van DKC, et al. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells, 2004, 22: 1338-1345. [19] Liu WH, Song FQ, Ren LN, et al. The multiple functional roles of mesenchymal stem cells in participating in treating liver diseases. J Cell Mol Med, 2015, 19: 511-520. [20] Ezquer F, Bahamonde J, Huang YL, et al. Administration of multipotent mesenchymal stromal cells restores liver rege-neration and improves liver function in obese mice with hepatic steatosis after partial hepatectomy. Stem Cell Res Ther, 2017, 8: 20. [21] 李兰娟. 中国人工肝研究——跟跑者迈向领跑者. 中国发明与专利, 2018, 15: 37-44. [22] Millis JM, Cronin DC, Johnson R, et al. Initial experience with the modified extracorporeal liver-assist device for patients with fulminant hepatic failure: system modifications and clinical impact. Transplantation, 2002, 74: 1735-1746. [23] Sakiyama R, Blau BJ, Miki T. Clinical translation of bioar-tificial liver support systems with human pluripotent stem cell-derived hepatic cells. World J Gastroenterol, 2017, 23: 1974-1979. [24] Mazariegos GV, Patzer JN, Lopez RC, et al. First clinical use of a novel bioartificial liver support system(BLSS). Am J Transplant, 2002, 2: 260-266. [25] Rhee CM, Ghahremani-Ghajar M, Obi Y, et al. Incremental and infrequent hemodialysis: a new paradigm for both dialysis initiation and conservative management. Panminerva Med, 2017, 59: 188-196. [26] 张悦. 新型生物人工肝免疫安全性的实验研究. 南京医科大学, 2012. [27] Shi XL, Gao Y, Yan Y, et al. Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes. Cell Res, 2016, 26: 206-216. |