[1] 陈海君,陈英刚,曹梅英,等.乙型肝炎肝纤维化患者肠道菌群结构及血清代谢谱的改变.中华临床感染病杂志,2013,6:343-346.
[2] Kakiyama G,Pandak WM,Gillevet PM,et al.Modulation of the fecal bile acid profile by gut microbiota in cirrhosis.J Hepatol,2013,58:949-955.
[3] Qin N,Yang F,Li A,et al.Alterations of the human gut microbiome in liver cirrhosis.Nature,2014,513:59-64.
[4] Bajaj JS, Heuman DM, Hylemon PB, et al. Altered profile of human gut microbiome is associated with cirrhosis and its complications.J Hepatol,2014,60:940-947.
[5] Vlahcevic ZR,Buhac I,Bell CC,et al. Abnormal metabolism of secondary bile acids in patients with cirrhosis. Gut,1970,11:420-422.
[6] Kakiyama G,Monteith P,Fuchs M,et al. Modulation of the fecal bile acid profile by gut microbiota in cirrhosis. J Hepatol,2013,58:949-955.
[7] Kim I,Inagaki T,Choi M,et al.Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine. J Lipid Res,2007,48:2664-2672.
[8] Nevens F,Andreone P,Mazzella G,et al.A placebo-controlled trial of obeticholic acid in primary biliary cholangitis. N Engl J Med,2016,375:631-643.
[9] Verbeke L,Farre R,Verbinnen B,et al.The FXR agonist obeticholic acid prevents gut barrier dysfunction and bacterial translocation in cholestatic rats.Am J Pathol,2015,185:4094-19.
[10] Deitch EA.Bacterial translocation of the gut flora. J Trauma,1990,30:S184-189.
[11] Teltschik Z,Wiest R,Beisner J,et al.Intestinal bacterial translocation in rats with cirrhosis is related to compromised Paneth cell antimicrobial host defense.Hepatology,2012,55:1154-1163.
[12] Gómez-Hurtado I,Santacruz A,Peiró G,et al.Gut microbiota dysbiosis is associated with inflammation and bacterial translocation in mice with CCl4-induced fibrosis.PLoS One,2011,6:e23037.
[13] Lazarevic V, Whiteson K, Hernandez D,et al.Study of inter- and intra-individual variations in the salivary microbiota.BMC Genomics,2010,11:523.
[14] Areias C, Sampaio-Maia B, Pereira Mde L,et al.Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome.Clinics,2012,67:1007e1011.
[15] Crump KE and Sahingur SE.Microbial nucleic acid sensing in oral and systemic diseases.J Dent Res,2016,95:17-25.
[16] Hajishengallis G. Immunomicrobial pathogenesis of periodo-ntitis:keystones,pathobionts,and host response.Trends Immunol,2014,35:3-11.
[17] Bartold PM, Van Dyke TE. Periodontitis: a host-mediated disruption of microbial homeostasis. Unlearning learned con-cepts. Periodontol,2013,62:203-217.
[18] Silva Santos PS, Fernandes KS, Gallottini MH.Assessment and management of oral health in liver transplant candidates.J Appl Oral Sci,2012,20:241-245.
[19] Aberg F,Helenius-Hietala J,Meurman J,et al. Association between dental infections and the clinical course of chronic liver disease. Hepatol Res,2014,44:349-353.
[20] Singhal S, Dian D, Keshavarzian A, et al. The role of oral hygiene in inflammatory bowel disease. Digestive diseases and sciences,2011,56:170-175.
[21] De Filippis F, Vannini L, La Storia A, et al. The same micro-biota and a potentially discriminant metabolome in the saliva of omnivore, ovo-lacto-vegetarian and vegan individuals.PLoS One,2014,9:e112373.
[22] Bashan A, Gibson TE, Friedman J,et al. Universality of human microbial dynamics.Nature,2016,534:259-262.
[23] Hezel MP and Weitzberg E.The oral microbiome and nitric oxide homoeostasis. Oral diseases,2015,21:7-16.
[24] Bajaj JS,Betrapally NS,Hylemon PB,et al. Salivary microbiota reflects changes in gut microbiota in cirrhosis with hepatic encephalopathy. Hepatology,2015,62:1260-1271. |
