关键词: 肝硬化失代偿期, 宫腔镜手术, 安全性

Abstract: Objective To investigate the safety and efficacy of hysteroscopic surgery in patients with decompensated liver cirrhosis.Methods The clinical data of hysteroscopic operations in patients with decompensated liver cirrhosis from October 2012 to November 2018 in our hospital were retrospectively analyzed. Perioperative indicators including operation time, intraoperative blood loss, postoperative hospitalization time and complications were recorded. Moreover, the laboratory examination including blood routine, liver function, biochemistry and coagulation function were monitored and compared before and after the operation. Results The operations were completed successfully in all the 45 patients. The mean operation time was (48.82 ± 38.40) minutes (ranged from 10 to 205 minutes). The mean intraoperative blood loss was (13.18 ± 35.04) ml (ranged from 2 to 100 ml). And the mean time of postoperative hospitalization was (3.78 ± 3.16) days (ranged from 1 to 13 days). The incidence of postoperative complications was 13.33% (6/45). The albumin level and platelet count were significantly lower postoperative than those preoperative [(32.04 ± 4.24) g/L vs. (33.95 ± 4.61) g/L, (67.58 ± 44.59) ×10⁹/L vs. (71.84 ± 44.45) ×10⁹/L, P<0.05].Conclusion It is safe and feasible for patients with decompensated liver cirrhosis to undergo hysteroscopic surgery on the basis of strict surgical indication, appropriate perioperative management, practiced hysteroscopic surgery skills, as well as emphasis on hemostasis and infection prevention.

Key words: Decompensated liver cirrhosis, Hysteroscopic surgery, Safety