[1] |
中华人民共和国国家卫生健康委员会医政医管局.原发性肝癌诊疗规范(2019年版). 中国实用外科杂志, 2020, 40:121-138.
|
[2] |
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma. J Hepatol, 2018, 69:182-236.
|
[3] |
钱相君, 曲春枫, 鲁凤民. 肝癌肿瘤标记物在超声筛查监测早期肝细胞癌中的作用不可或缺. 肝脏, 2019, 24:851-853.
|
[4] |
Yao M, Zhao J, Lu F. Alpha-fetoprotein still is a valuable diagnostic and prognosis predicting biomarker in hepatitis B virus infection-related hepatocellular carcinoma. Oncotarget , 2016, 7:3702-3708.
|
[5] |
Arechederra M. New warning signs on the road: 5-hydroxymethylcytosine-based liquid biopsy for the early detection of hepatocellular carcinoma. Gut, 2019, 68:2103-2104.
|
[6] |
Xu RH, Wei W, Krawczyk M, et al. Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma. Nat Mater, 2017, 16:1155-1161.
|
[7] |
Tahiliani M, Koh KP, Shen Y, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science, 2009, 324:930-935.
|
[8] |
Dor Y, Cedar H. Principles of DNA methylation and their implications for biology and medicine. Lancet, 2018, 392:777-786.
|
[9] |
Yang H, Liu Y, Bai F, et al. Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene, 2013, 32:663-669.
|
[10] |
Liu J, Jiang J, Mo J, et al. Global DNA 5-Hydroxymethylcy-tosine and 5-Formylcytosine Contents Are Decreased in the Early Stage of Hepatocellular Carcinoma. Hepatology, 2019, 69:196-208.
|
[11] |
Cai J, Chen L, Zhang Z, et al. Genome-wide mapping of 5-hydroxymethylcytosines in circulating cell-free DNA as a non-invasive approach for early detection of hepatocellular carcinoma. Gut, 2019, 68:2195-2205.
|
[12] |
Song CX, Szulwach KE, Fu Y, et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcy-tosine. Nature Biotechnol, 2011, 29:68-72.
|
[13] |
Song CX, Yin S, Ma L, et al. 5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages. Cell Res, 2017, 27:1231-1242.
|
[14] |
Bhattacharyya S, Pradhan K, Campbell N, et al. Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways. Genome Res, 2017, 27:1830-1842.
|
[15] |
Hayashi PH, Rockey DC, Fontana RJ, et al. Death and liver transplantation within 2 years of onset of drug-induced liver injury. Hepatology, 2017, 66:1275-1285.
|
[16] |
Hu Y, Ulrich BC, Supplee J, et al. False-Positive Plasma Genotyping Due to Clonal Hematopoiesis. Clin Cancer Res, 2018, 24:4437-4443.
|