粪便微生物群移植在肝性脑病治疗中的研究进展

摘要/Abstract

摘要： 肝性脑病(hepatic encephalopathy,HE)是终末期肝病患者住院和死亡的重要原因,目前可用的治疗选择比较有限。近年来,研究表明肠道微生态在HE中发挥了重要作用,粪便微生物群移植 (fecal microbiota transplantation, FMT) 在HE中的应用成为新的研究热点。本综述旨在总结支持FMT在HE中的安全性、有效性和未来前景的最新研究进展。尽管仍存在着FMT的给药方案、长期效果和最佳供体的选择等问题,但当前的研究结果表明FMT是一种安全、有效和可耐受的HE治疗手段,希望未来可以为我们提供更多的证据。

关键词: 粪便微生物群移植, 肝性脑病, 肝硬化, 肠道微生态

徐圣, 翁丹萍, 曾玥, 岳海燕. 粪便微生物群移植在肝性脑病治疗中的研究进展[J]. 肝脏, 2023, 28(7): 872-874.

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