关键词: 麻疹, 肝生化指标异常, 丙氨酸氨基转移酶, 预后

Abstract: Objective To explore the clinical characteristics and prognosis of patients with measles combined with liver dysfunction, and to improve diagnostic and treatment capabilities. Methods A total of 182 patients diagnosed with measles admitted to our hospital from January 2013 to June 2023 were selected as the study subjects, divided into an adult group and a children′s group, and all case data were statistically analyzed. Results There were a total of 27 cases with abnormal liver function, accounting for 14.8%. There were 21 cases in the adult group and 6 cases in the children′s group, with no significant difference (P>0.05); Abnormal liver function was found during the rash period, with most cases showing no obvious discomfort symptoms; All 27 patients had elevated ALT levels, with an average of 106.6 ± 42.8 U/L, compared to 109.3 ± 58.5 U/L in the adult group and 98.5 ± 44.2 U/L in the children group, with no significant difference (P>0.05). 14 patients had elevated AST levels, but no patients had elevated bilirubin levels; Liver injury was classified as mild in 25 cases, moderate in 1 case, and severe in 1 case. After appropriate liver protection treatment, 22 cases were cured, 5 cases improved, and 0 cases were ineffective. The effective rate was 100%. Conclusion Abnormal liver function is a common complication of measles observed in adults and children. It is more likely to occur during the rash period, and the clinical symptoms are not obvious. It is mostly mild to moderate damage, with elevated ALT as the main symptom. It can be cured through appropriate liver protection treatment.

Key words: Measles, Abnormal liver function, Alanine aminotransferase, Prognosis