肝脏 ›› 2025, Vol. 30 ›› Issue (7): 917-921.

• 肝纤维化及肝硬化 • 上一篇    下一篇

肠道菌群与肝性脑病相关性研究的文献计量及可视化分析

曹艳梅, 马素平, 肖准   

  1. 450003 河南郑州 河南中医药大学第一附属医院脾胃肝胆科(曹艳梅,马素平,肖准);450000 河南中医药大学第一临床医学院(曹艳梅)
  • 收稿日期:2024-07-30 出版日期:2025-07-31 发布日期:2025-08-11
  • 通讯作者: 马素平,Email:masuping@163.com
  • 基金资助:
    国家自然科学基金青年基金(82104772),中国博士后科学基金(2022M721067),河南省科技攻关计划(222102310502),河南省科技研发计划联合基金(222301420062),河南省中医药科学研究专项(2022ZY2008);河南省中医学“双一流”创建科学研究专项课题(HSRP-DFCTCM-2023-3-20),河南省特色骨干学科中医学第二批学科建设项目(STG-ZYX02-202109)。

Bibliometric and visual analysis of studies on the correlation between gut microbiota and hepatic encephalopathy

CAO Yan-mei1,2, MA Su-ping1, XIAO Zhun1   

  1. 1. Department of Hepatology and Spleen - Stomach, the First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450003, China;
    2. The First Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China
  • Received:2024-07-30 Online:2025-07-31 Published:2025-08-11
  • Contact: MA Su-ping,E-mail:masuping@163.com

摘要: 目的 分析近20年肝性脑病与肠道菌群相关性的研究现状、热点及前沿趋势。方法 检索Web of Science核心数据库2004年1月1日至2023年12月31日的肝性脑病与肠道菌群相关性研究的英文文章。通过文献计量分析软件VOSviewer分析发文国家、机构、作者和研究领域的热点和前沿方向。结果 共检索到681篇文章,发文量呈逐年增长的趋势,Virginia Commonwealth University为发文量最多的机构,美国、中国、意大利是发文量最多的国家,国外学者Jasmohan S.Bajaj发文量最高,《World Journal of Gastroenterology》为该领域发表数量最多的期刊。结论 通过对肝性脑病与肠道菌群相关性研究进行可视化分析,发现研究热点主要集中在肝性脑病、肠道菌群、肝硬化和菌群失调等方面。

关键词: 肝性脑病, 肠道菌群, 文献计量学, 可视化分析

Abstract: Objective To analyze the research status, hot spots and frontier trends of the correlation between hepatic encephalopathy and gut microbiota over the past 20 years. Methods English literatures on the correlation between hepatic encephalopathy and gut microbiota were searched from the Web of Science (WOS) core database from January 1, 2004 to December 31, 2023. The bibliometric analysis software VOS viewer was used to analyze the countries, institutions, authors and hot spots and frontier directions in this research field. Results A total of 681 articles were retrieved, and the number of papers published gradually increased, Virginia Commonwealth University was the largest institution contributing to these publications. The United States, China and Italy were the largest countries, Bajaj JS was the highest author, and the《world journal of gastroenterology》was the most published journal in this field. The research focus can be summarized as hepatic encephalopathy, gut microbiota, liver cirrhosis, flora disorders and so on. Conclusion Through visual analysis of the hot spots and emerging trends in the study of the correlation between hepatic encephalopathy and gut microbiota, a more comprehensive reference was provided for the research in this field.

Key words: Hepatic encephalopathy, Gut microbiota, Bibliometrics, Visual analysis