慢加急性肝衰竭的全球性研究进展

肝脏 ›› 2022, Vol. 27 ›› Issue (7): 729-732.

慢加急性肝衰竭的全球性研究进展

姜绍文, 谢青

200025 上海交通大学医学院附属瑞金医院感染科

收稿日期:2022-06-10 出版日期:2022-07-31 发布日期:2022-08-25
通讯作者: 谢青,Email:xieqingrjh@163.com
基金资助:
上海市临床重点专科(感染病学)( shslczdzk01103);国家自然科学基金(81770587,82070604,82000588);“十三五”科技部重大专项 (2017ZX10203201-008, 2018ZX09201016-003-001, 2017ZX10202202-005-004)

Received:2022-06-10 Online:2022-07-31 Published:2022-08-25

摘要/Abstract

摘要： 慢加急性肝衰竭(ACLF)是一组在慢性肝病基础上受到急性肝内外损伤因素打击而导致多器官功能衰竭的临床综合征,早期死亡率高,是临床需要面对的一大难题,也是近年来肝病学界研究的热点。几大国际肝病学会已提出不同的ACLF诊断标准及基于各自标准的诊疗共识。然而由于不同地区肝脏疾病病因和诱因存在鲜明的区域性特征,通向全球统一的ACLF定义、同质化和标准化的临床管理共识的道路任重而道远。目前ACLF领域内的研究呈现“百家争鸣、百花齐放”之势,本文拟对近期关于ACLF研究的新进展、新证据作一总结,以期促进学术交流、推动学术发展。

关键词: 慢加急性肝衰竭, 流行病学, 肝硬化, 急性失代偿, 非急性失代偿, 诱因

姜绍文, 谢青. 慢加急性肝衰竭的全球性研究进展[J]. 肝脏, 2022, 27(7): 729-732.

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