特利加压素治疗肝肾综合征-急性肾损伤的研究进展

摘要/Abstract

摘要： 肝肾综合征-急性肾损伤(HRS-AKI)是失代偿期肝硬化患者一种少见的肾损伤类型,病死率高。肝移植(LT)是HRS的根治性疗法,血管收缩剂联合静脉白蛋白是其支持治疗的基石。特利加压素是一种作用于内脏循环的V1a受体激动剂,近期获得美国食品药品监督管理局(FDA)批准,引发了业界对这类药物的新关注。本文回顾了HRS的病理生理学特点和诊断标准、特利加压素的临床应用及替代疗法,并探讨了HRS-AKI的未来研究方向。

关键词: 特利加压素, 肝肾综合征, 急性肾损伤, 肾脏替代治疗, 肝移植

宦红娣, 闫晗, 陆春来. 特利加压素治疗肝肾综合征-急性肾损伤的研究进展[J]. 肝脏, 2025, 30(8): 1032-1035.

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